Why treatment of candida biofilms is a necessary aspect for effective treatment of systemic yeast overgrowth and which biofilm disruptors are best for the fastest resolution of symptoms.
Yeast overgrowth, also referred to as fungal overgrowth or simply Candida, is at epidemic levels today.
This is true whether a person understands it to be a serious threat to health or not.
Most symptoms that indicate fungal overgrowth in one or more body tissues are usually treated by conventional doctors as another condition entirely. Thus, the root cause is never actually addressed.
Even holistic doctors can miss the mark by not considering the importance of breaking down biofilms as part of an effective candida treatment plan. This can ultimately lead to failure of the protocol and much frustration on the part of the patient.
Symptoms of Yeast Overgrowth (aka “Candida”)
There are a number of common symptoms that can indicate a problem with yeast overgrowth. The signs from these various strains of candida including the super-fungus Candida auris include:
- headaches (including brief “ice pick” headaches)
- skin rashes such as acne and eczema
- mucous build up in the throat nose and lungs
- sinus infections
- Itchy inner ears and skin
- Itching genital infections
- athlete’s foot
- nail fungus (usually occurring in the toenails).
If chronic, yeast overgrowth can affect the nervous system leading to many cognitive symptoms such as:
- brain fog
- poor concentration
- anxiety
- depression
- mood swings
Opportunistic yeast such as candida are organisms that normally exist harmlessly as a normal part of our internal environment.
They do not cause harm until they outgrow the good bacteria that keep balance and harmony within the body, which also keeps the immune system functioning properly.
At this point is when fungal overgrowth can wreak havoc, disrupting the immune system and progressively leading to one or more of the above symptoms.
Causes of Systemic Fungal Infections
Opportunistic bacteria and yeasts like Candida albicans don’t just spontaneously “take over”.
There’s a reason this happens!
I prefer to group these causes into three main categories: stressful lifestyle, poor diet, and pharmaceutical drugs (not just antibiotics) have a powerful impact on our gut flora providing the opening for opportunistic strains of yeast to exert authority and overgrow with dire health consequences over time.
- Diet– A diet high in sugar, starch and processed foods is fuel for yeast to thrive and multiply. One study found that biofilms of Candida are made of 32% glucose. It was found that Candida yeast needs sugar not just to reproduce, but also to create the protection in the form of a biofilm that keeps our immune system from attacking it. (1)
- Lifestyle- A stressful lifestyle can lower immunity and therefore lead to a decrease in beneficial gut flora. Remember 80% of immunity is located in the gut. Keeping bacteria in check is crucial to keeping symptoms and sickness at bay. Other factors that can lead to yeast overgrowth is exposure to chlorinated water, alcohol abuse, and digestive distress coming from a lack of stomach acid (hydrochloric acid) which causes undigested food to putrefy in the gut, leading to symptoms such as constipation and diarrhea.
- Drugs- Antibiotics and the birth control pill contribute to systemic candida in a big way. These pharmaceuticals eliminate beneficial flora creating the ideal environment which allows for harmful pathogens to overgrow and take over from beneficial microbes.
Gut Flora and the Skin
Since the majority of my focus in nutrition is on skin issues, about 95% of my clients have digestive concerns and almost always have some extent of dysbiosis (imbalance of gut bacteria), and of course, yeast or other microorganisms that need to be treated.
Beyond addressing the three main categories above, eradicating these critters is necessary to see lasting improvements in skin symptoms, whether it’s histamine-triggered acne or eczema.
Eliminating Biofilms Most Effective Treatment
Much of the information regarding yeast and candida out there addresses treatment, including diet and supplements, although leaves out a very crucial step.
There’s another side of the story that rarely gets talked about that can make all the difference.
Biofilms act as a protective shield around yeast and other microorganisms. This makes it more challenging to attack the yeast, as the antifungals usually cannot get through this matrix.
This is the case whether the antifungal is herbal or pharmaceutical.
This is how yeast hides and protects itself from being destroyed.
One study of a group of anti-fungal drugs, including Nystatin and Diflucan, found that they were initially effective until the biofilm developed. (2)
At this point, they became less effective, and after 72 hours of biofilm development, the candida cells were highly resistant.
This research indicates that drug resistance develops over time due to biofilm development. Now researchers are seeing more common anti-fungal drugs such as amphotericin B and fluconazole developing resistance as well.
Using Enzymes to Attack Yeast Biofilms
Common natural antifungals used in yeast overgrowth treatment include oregano oil, garlic, black walnut, uva ursi, berberine, and olive leaf among others. However, these alone won’t do the trick.
To properly get to and kill the microorganism that is causing the trouble, you first have to break down the biofilm that’s protecting it.
Think of it as attempting to get past a security guard. It’s possible to get through him, you just need a more comprehensive approach to ensure your game plan is effective.
Anti-fungals need to be paired with a biofilm disruptor to be most effective.
This is a combination of specific enzymes that are designed to eat their way through their matrix of protection.
Candida and other types of yeasts have no resistance and are not able to build a resistance to enzymes like they may be able to do with drugs or herbs. There are no side effects, only side benefits with this type of biofilm disruptor.
When looking for an enzyme formula (I like this one) make sure and find one that contains a varied number of enzymes to target the layer of the cell wall, biofilm, nucleus, and fibrin.
Enzymes to look for specifically in a product are cellulase, glucoamylase, amylase, invertase, protease, and serrapeptase.
Amino Acid (NAC) an Effective Biofilms Disruptor
Another agent that has been studied to also be effective as a biofilm disruptor is N-Acetyl cysteine (NAC).
NAC is an amino acid and a strong antioxidant but also has antibacterial properties. Tested on several different bacteria species, it has shown to be effective, especially in upper respiratory infections including Covid and its many mutations. (3, 4)
Because of the number of relapses in both bacterial and yeast issues, alternative treatments as these biofilm agents provide are needed to complete eradication.
I suggest working with a holistic health care practitioner who has experience treating yeast overgrowth to get an effective treatment plan.
This is why an anti-yeast/candida type diet can be difficult and usually not enough. You have to get the support to address the cause effectively otherwise you may not be seeing the results you’re after.
(1) Biofilm matrix of Candida albicans and Candida tropicalis: chemical composition and role in drug resistance
(2) Biofilm Formation by the Fungal Pathogen Candida albicans: Development, Architecture, and Drug Resistance
(3) Anti-Biofilm Activity of N-Acetylcysteine as Demonstrated by Confocal Laser Scanning Microscopy
(4) N-acetylcysteine (NAC) inhibit biofilms produced by Pseudomonas aeruginosa
More Information
Pau d’Arco for Candida
Can Candida Sufferers Drink Kombucha?
How to Take Probiotics
Anonymous
I just ordered the interfase plus – how do you take it and for how long and when do you start antifungals? Any guidance is appreciated!
Sandi Hall
These sound very effective, but I have an added problem- I have a swallowing issue, and cannot take pills or capsules. Is there a liquid or chewable solution?
Toni
Try opening the capsule and sprinkling the contents onto a spoonful of applesauce, yogurt, or pudding for easier swallowing. I don’t know how severe your swallowing disorder is, but some people also have luck dipping hard-to-swallow-pills into olive oil or vegetable oil to make them slide down easier and decrease the chance of it hanging in the throat.
paytin
I agree – sticking with the Candida Diet is the best way to go. I wish I had that will power all the time! The Candida Diet def works, but i also keep a bottle of Lady Soma Candida Cleanse handy when I cant follow the diet – take a pill in the morning and at night for a couple days – and it will be gone…..get back on the diet when you can – but keep Lady Soma around when you cant
Stephanie
I have 13 month old twins who were born 9 weeks early and spent 6 weeks in the NICU after birth. Currently they both have really bad yeast infections in their diaper areas. They’ve had it for a long time, but now it is really bad. The nystatin that the doctor perscribed isn’t helping at all. Well, maybe it did at first, a little. Is there an enzyme you would recommend for them to break down the biofilm?
monica
do you recommend probiotics during the biofilm/anti-fungal treatment or after?
Dana T
I use the Interphase Plus. Klaire also makes a plain Interphase, but the “Plus” includes EDTA, a heavy metal chelateor. Research has shown that bacteria and virus’s have an affinity with heavy metals and to properly remove either, both have to be addressed.
Good article, thanks.
Debbie
High dosage probotic, plenty of water and VICKS VAPOR RUB on areas where yeast infection arises. Tried everything!!! It seems hard for some people to believe, just try it… you don’t have anything to loose and everything to gain!!! Live a yeast infection free life!!!
Stan Bell
Thanks for sharing and I just bookmarked your blog. Just checked your other posts as well and I enjoyed reading them. They’re all very informative. I must admit that I’m not good with all the nutritional stuff. I look forward to reading your future posts. Thanks again, Carla. Cheers!
Natalie
Hello Carla, I have stumbled onto what Candida overgrowth is and i have realized i have pretty much all symptoms. I didn’t know that all of the symptoms i was experiencing was coming from a source of Candida overgrowth and it all makes sense to me now as to why i have been suffering for years. I have had allergies all my life, ear infections, fungal skin issues(athletes foot, ring worms) acne has been an ongoing problem for as long as i can remember. I also experience chronic sinusitis yearly, which only seem to be relieved with antibiotics , which i now know have been a contributing factor to my issues and cause more harm than good. The newest thing is overactive bladder symptoms that have lasted for years and yeast infections. I started to take a multivitamin called Vitamin code for women and i noticed that i started to feel very good with lots of energy. Then out of no where my acne issues worsened like never before and exploded into cystic acne all over my cheeks and other places. I was so upset with all the acne that i stopped taking the Vitamin Code woman’s multivitamin because i was convinced that these multivitamins were overloading my system and causing the issues. I now wonder if the side effects i was experiencing were related to a detox in my system because of the Candida overgrowth?? These Multivitamins have raw probiotic and Enzyme blend in them with all of the biofilm enzymes you have mentioned in your article a long with numerous minerals and vitamins present. Was this a die off of the candida and candida biofilm that i was experiencing?
Kristen
I’ll bet you were having die-off symptoms. I’ve been fighting yeast for over 10 years. I started taking a double dose of a probiotic with an enzyme for the biofilm and it got way worse for a while. But now it is much improved.
Carole from France
Thanks so much Carla for this enlightening post ! I have a question though : InterFase plus contains EDTA which chelates heavy metals, including possibly mercury. Is it safe to use when you still have mercury containing amalgams in your mouth ? (For the time being I cannot have them removed properly) Would it be wiser to take InterFase instead?