There seems to be a lot of confusion surrounding the topic of hydrolyzed collagen, also commonly called collagen hydrolysate. This is especially true with regard to how it compares with a closely related food known as gelatin.
For example, I’ve had an increasing number of emails from people who have attempted to make homemade jello, mousse or similar recipes and inadvertently used hydrolyzed collagen instead of gelatin.
As a result, the recipe ended up being a total fail because hydrolyzed gelatin does not congeal liquids at all. This compares with a single tablespoon of gelatin which is enough to firmly set 2 cups of liquid.
This mistake is very easy to make because gelatin and hydrolyzed collagen look and taste almost exactly the same. This is due to a very similar amino acid profile.
Part of the confusion is a simple case of semantics. Let’s clear that up first.
The Many Names of Hydrolyzed Collagen
The names used to refer to hydrolyzed collagen are many. So that you don’t ever confuse it with its similar cousin, gelatin (aka collagen protein), and mess up a recipe (real food ingredients are expensive!), be sure to make a mental note of these commonly used aliases:
Common Names for Hydrolyzed Collagen
- Collagen hydrolysate
- Hydrolyzed gelatin
- Hydrolyzed gelatine (the UK and Australia)
- Hydrolyzed gelatin(e) collagen
- Collagen peptides
- Peptides
- Hydrolyzed Collagen Protein
- Hydrolyzed Collagen Peptides
Have you come across other nicknames for hydrolyzed collagen? If so, please let us know in the comments section.
What Exactly -IS- Hydrolyzed Collagen?
The benefits of gelatin as a traditional food are many. To start with, it has powerful anti-inflammatory and anti-aging qualities (vetted sources). It does an amazing job of helping to fill in the missing amino acids (the building blocks of proteins) in the diet. This is especially important if you don’t include much (or any) bone broth in your diet, are vegetarian, or have a lifestyle which makes it difficult to eat a balanced, ancestral diet that makes a point of prioritizing “nose to tail” eating (using the whole animal for food and not just the muscle meat) like traditional cultures frugally practiced out of necessity.
Gelatin has a unique amino acid profile, primarily consisting of glycine, glutamic acid, proline, and alanine. It is derived from the connective tissues of animals, either cattle, pigs or fish. In bovine gelatin, the collagen comes from the tissue just underneath the hair found on the hide of the animal.
Although the amino acids in gelatin are non-essential (meaning your body is able to make them), many nutritionally deficient and overly stressed people are not able to manufacture them in the amounts demanded by the body for optimal health. The liver needs an abundance of these amino acids to keep functioning at a high level, particularly to fuel detoxification which has the benefit of reducing inflammation.
As a food, hydrolyzed collagen is very similar to gelatin, but there are critical differences.
This is because the manufacturing of hydrolyzed collagen is more intensive than the processing of gelatin. Hydrolyzed collagen manufacturing breaks up the amino acid chains (protein) into smaller units than the processing of gelatin.
Thus, while the amino acid profiles and health benefits between hydrolyzed collagen and gelatin are similar, the chemical properties such as the ability to set liquid, are quite different. In addition, the digestibility of hydrolyzed collagen appears to be superior for some people due to the less complex structure.
Hydrolyzed Collagen in the Research
Consumer interest in hydrolyzed collagen has exploded in recent years due to a growing body of research that suggests it has powerful anti-aging properties for skin, bone, and joints.
It is well known that collagen is an important building block for the body’s connective tissues, helping them maintain strength and elasticity (1).
The Journal of Agriculture and Food Chemistry built upon this foundational research showing that when a person orally consumes collagen hydrolysates, blood levels of the peptide form significantly increased and reached maximum levels after 1-2 hours. After that, blood levels decreased to half of the maximum level 4 hours after ingestion (2).
Does this increase in blood levels of collagen peptides actually benefit connective tissues, however? Again, research suggests this is so. The Journal of Nutritional Science and Vitaminology published a study where researchers demonstrated that the ingestion of collagen peptides beneficially affects the size and composition of collagen fibrils in the Achilles tendon thus potentially improving its mechanical properties (3).
What about bone health? Animal studies on collagen peptides suggest that oral consumption of hydrolyzed collagen may benefit bone health in both males and females even in a calcium-deficient state (4).
Another clinical study published in the periodical Seminars in Arthritis and Rheumatism examined the ingestion of 10 grams of collagen peptides per day for a period of 30-90 days. A positive effect on knee joint comfort was noted and the effect was even more pronounced in patients suffering more severe symptoms (5).
The most compelling research of all?
The journal Skin Pharmacology and Physiology published a “gold standard”, double-blind, placebo-controlled study in 2014 which demonstrated a causal relationship between a 12-week daily regimen of orally consumed hydrolyzed collagen and significantly improved skin elasticity, structure, and moisture (6).
This study gives concrete evidence as to the likely reason why ancestral peoples maintained such a youthful countenance into middle and old age. It wasn’t just less stress and lots of fat-soluble vitamins (especially vitamin K2) although this certainly helped. It was also at least partially due to the collagen in their diet from the traditional practice of nose to tail eating. This has been de-prioritized in the modern diet as the popularity of processed foods and a disposable, throw-away mentality steadily advanced since World War II.
Which Type of Hydrolyzed Collagen is Best?
There are two different types of hydrolyzed collagen currently on the market.
One type is derived from pasture-raised beef and the other from sustainable, wild-caught marine sources verified to be GMO-free.
I have tried both types of hydrolyzed collagen and can honestly say that I have a hard time telling the difference between them except for the slightly off white color of the pasture-raised peptides, which you can see in the picture above.
Quality Collagen is Tested for Purity
I’m going to give you a critical piece of advice when buying peptides.
Do not buy ANY brand unless it is tested for purity and glyphosate residue. I have personal knowledge of some collagen brands testing very high in glyphosate. Thus, making sure the one you use is certified pure is very important.
Please note that the brands I suggest are tested to ensure no toxic residues are present!
Using Peptides
Both the marine collagen and pasture-raised collagen peptides blend nicely in hot or cold foods like a smoothie, have a similar nutritional profile and digest very well.
It is very important to ONLY buy from brands that have independently tested and verified that their grass-fed collagen is free of glyphosate residue, a huge problem for these types of products that concentrate animal tissue.
Currently, only this brand is independently tested/verified to be residue-free.
Ultimately, the brand you choose to use in your home can be based on budget and food philosophy. If you are vegetarian, for example, you will likely prefer a marine sourced collagen peptide. This stuff is amazing … it has no fish smell. Even my daughter who is very averse to anything fishy tasting or smelling couldn’t tell the difference when I stirred some into a glass of fresh OJ.
As for me, I have both types of collagen hydrolysate in my pantry and rotate them.
Why?
Well, I don’t eat beef or fish 7 nights a week, and I would guess that your family probably doesn’t either. So why not use both of the available types of collagen peptides too if they are available?
Of course, I have no scientific basis for this personalized approach. It’s just what I do in my home, and I share that with you for what it’s worth.
The point is, hydrolyzed collagen is a beneficial food to health and incorporating it into your diet is helpful and supported by scientific research.
Contraindications
As with anything, remember not to get too carried away with hydrolyzed collagen if you choose to use it in your diet. It’s not a silver bullet for everything that ails you! Go slow when introducing your body to this wonderful food. Like with probiotics, kefir, kombucha and other traditional foods you may not be used to, adding too much too quickly can cause digestive issues like bloating or stomach ache.
If you’ve already tried hydrolyzed collagen, which type do you prefer, pasture-raised or marine? Can you tell a difference and how do you use it?
Gloria Lusiak
THANK YOU for being who you are. I am a health research freak and now need to know of your opinion on Collagen. There is a person that you regard highly as stated on your website that feels UNHYDROLIZED collagen is best. Please take a look at Dr. M.’s site and let me know what you think regarding quality. I would post a link but thought you may not approve. He says: A recent debate surrounding collagen is the hydrolyzed vs. unhydrolyzed issue. With hydrolyzed collagen products, harsh processing breaks down or “isolates” peptides to boost bioavailability.
I prefer using a less denatured or unhydrolyzed organic collagen supplement, as it has a more balanced and complete amino acid profile. Many people don’t realize it, but unhydrolyzed whole-food collagen contains these isolated peptides, too.
THANK YOU!!
Meredith
Thank you so much for your reply Sarah! I really appreciate it 🙂 Blessings!
Meredith
Hi Sarah, Do you recommend the Vital Proteins brand collagen (is it roundup free, safe, non toxic?) or do you think the Perfect Brand hydrolyzed collagen is the safest brand to consume? Just trying to wrap my head around which one is safest to use for my family! Thanks
Sarah Pope MGA
I use and recommend Perfect Supplement’s brand of hydrolyzed collagen because it is currently the only one that is certified glyphosate free by an independent third party. It is also way cheaper than Vital Proteins if you buy in bulk. https://www.perfectsupplements.com/Perfect-Hydrolyzed-Collagen-p/ps-collagen.htm/?Click=5d71106181757
Steve
Excess Glutamate in the brain causes calcium channels to stay firing, sodium has nothing to do with it’s excitotoxic properties. I don’t believe the added hydrogen to glutamic acid really changes much, in biochemistry it’s interchangeable because the way the react in the body is the same. What am I missing here?
Kimberly Runnels
I have gout and arthritis, so I must limit beef intake. Would taking collagen affect my gout and arthritis? Thank you!
Sarah Pope MGA
You can get marine collagen. Perhaps that would be best for your situation.
Jill
So what brands do you recommend?
Sarah Pope MGA
There are links in the article to the brand I use. https://www.radiantlifecatalog.com/category/s?keyword=collagen+peptides&a=58537
JohnTaylorHK
Of course, most such articles are intended to make you buy supplements etc. Get 12 chicken feet (cheap hear in Manila) or some beef bones (Bulalo!) put them in your slow cooker and cover with potable water. Add one tbsp of vinegar. Heat on high for 2-4hrs and then leave on auto/low until the feet break up when you stir the liquid. If you are a frequent “peeker”, you may need to add the water you allowed to boil off whilst you were peeking. Strain the liquid into a container and allow to cool. It will set (if you didn’t put an excessive amount of water in) into a beautiful gelatin. Cut into chunks and put a chunk into some hot water. Stir until gelatin is dissolved, add salt to taste, drink. Job Done! Namaste!
Sue Binnie
my osteopath is suggesting hydrolysed collagen to improve my Achilles heel aches. I don’t run as an exercise option, but walk the dog daily and don’t always wear ‘proper’ running shoes. what’s your opinion?
Mildred Susan Wells
You need to supplement with K2, preferably a D3/K2 supplement. K2 is the vessel directing calcium from your foods to required areas within the body preventing a buildup in your heart and other areas not supported by calcium. Don’t supplement with calcium.
bbh999
Sarah,
Very informative article, but it seems from the information here that there is no practical or important dietary difference between hydrolyzed collagen and plain ol’ gelatin. I’ll forego the hydrolyzed collagen and stick with bone broth and gelatin. One less cult to belong to.