Did you know acne is the most common skin disorder in the United States, affecting 40 to 50 million Americans?
Nearly 85 percent of all people will have acne at some point in their lives. It can generally begin in the teen years, with more than 40 percent of adolescents being affected due to puberty and hormonal changes, and although it is generally seen as a teenage phase, this couldn’t be further from the truth.
More than 90% of clients I work with struggling with acne are over 30 years old. For some it does go away, and for others it stays, and for many, the first time they experience acne may not be until later in life, from late 20’s to even 50 years of age.
Acne affects individuals not just physically, but emotionally as well. The notion that acne is just a “cosmetic problem” is very off base. Acne is a reflection of something greater happening in the body that is not being corrected. Therefore, the skin continues to lash out in an effort to communicate that there is an imbalance, deficiency, or the mechanics within are just not working as they should be. But this takes time to figure out, and unfortunately, our conventional way of addressing acne tries to do this immediately with topical treatment and/or pills.
Though no matter what age acne occurs, the one thing everyone will feel as a result is pain and embarrassment. Acne affects an individuals confidence, mental outlook, and can greatly impact one’s social life. According to the American Academy of Dermatology, one in five U.S. adults also suffers from acne, and for them the psychological toll is often no less severe.
So the question then becomes: How far would you go to get rid of your acne?
Would you compromise your health for clear skin? Would you gain more weight, lose your concentration, vision or appetite? How about put your unborn baby at risk for severe health consequences? Sounds crazy right? If you have ever experienced acne, you know the desperation one feels, literally being at your wits end to find an answer.
Once the topical products and treatments stop working (or may never have), it’s quite normal to start looking for other options. Go to your doctor or dermatologist, like most people, and you may find they prescribe a little drug called Accutane.
Accutane: The Most Dangerous Drug Ever Created?
Actually, this is no little drug at all, and definitely not something to just accept and take lightly.
The generic name is sold as, isotretinoin, and formerly marketed as Accutane (Roaccutane outside the United States). Other generic forms of Accutane are Claravis, Sotret and Amnesteem. Accutane is part of a class of medications that were originally marketed as chemotherapy drugs. The generic versions of Accutane are just as dangerous as the original.
The medication is a synthetic derivative of vitamin A and works by controlling the oil in the sebaceous glands for those who have not responded to antibiotic treatment.
In 1975 American researchers for Hoffmann-La Roche began studying the chemical, isotretinoin, and found it to be an extremely powerful antidote to acne, unmatched by any other treatment. They found that 85% of patients who took Accutane achieve full remission after a typical course of treatment (about five months). FDA Consumer Magazine pronounced it as “the biggest breakthrough in acne drug treatment over the last 20 years.” It was, and still is seen as a “miracle drug”, but at what cost?
Accutane Side Effects
The U.S. Food and Drug Administration stated:
All patients treated with isotretinoin [Accutane] should be observed closely for symptoms of depression or suicidal thoughts, such as sad mood, irritability, acting on dangerous impulses, anger, loss of pleasure or interest in social or sports activities, sleeping too much or too little, changes in weight or appetite, school or work performance going down, or trouble concentrating, or for mood disturbance, psychosis, or aggression.
Other side effects include:
- Diminished night vision
- Increased bone injuries and concussion risk due to weakened bones
- Severe joint and muscle pain
- Liver damage
- Autoimmune disease
- Red, cracked or sore lips
- Brittle nails
- Unusual hair growth or hair loss
- Fatigue
- Headaches
- Increased reaction to UV exposure
- Nosebleeds
- Peeling skin
- Bleeding or swollen gums
- Slow healing of cuts or bruises
- Dry eyes
- Muscle aches
- Increase susceptibility to colds
- IBS
- Depression
- Aggressive Behavior
- Suicide
- Guaranteed birth defects
Drugmaker, Roche, who created the original version of Accutane has had 13 lawsuits from users who developed inflammatory bowel disease as a result of taking Accutane. In addition, it has been showed in brain scans that there was a 21% decrease in brain activity, leading to depression, suicide and aggressive behavior.
Accutane, which is currently no longer on the market, was only meant to be used as a last resort to treat acne, but prescriptions of its competitors and generic versions are just as health damaging and are being offered for even acute cases of a few spots.
Accutane Heavily Overprescribed Under Different Names
Remember, generic forms of Accutane are still on the market and heavily overprescribed. They are listed as Isotretinoin (originally Accutane), Claravis, Sotret and Amnesteem and are just as deadly.
According to Jennifer Hansen, a 21 year-old taking Accutane who keeps an online Accutane journal, “This medicine has given me my life back. . . . I am now confident, happy and very excited about life. I no longer feel inferior and can actually look people in the eyes.”
This statement sounds like a contradiction knowing the dangerous potential that Accutane has to destroy lives. If Jennifer had tried other natural methods that addressed her real cause of acne, she may have truly gotten her life back, both in clear skin and health, but unfortunately for those who have used Accutane, the consequences may not come until later in life.
Accutane: FDA Pregnancy Category X
The deadliest side affect of them all was announced when the FDA slapped the strongest warning available, as an FDA Pregnancy Category X rating, GUARANTEEING that whether you are pregnant or will become pregnant, taking Accutane can cause birth defects, miscarriage, and death in babies.
According to Julia Green, who wrote the article, “A History of Accutane Regulation in the United States” through Harvard Law School, “One quarter of babies born who have been exposed to Accutane during gestation have major congenital deformities. Those babies born without major malformations frequently develop severe learning disabilities.”
Is this not reason enough to avoid this drug?
According to the FDA’s iPledge system:
There is an extremely high risk that severe birth defects will result if pregnancy occurs while taking isotretinoin in any amount, even for short periods of time. Birth defects which have been documented following isotretinoin exposure include abnormalities of the face, eyes, ears, skull, central nervous system, cardiovascular system, and thymus and parathyroid glands. Cases of IQ scores less than 85 with or without other abnormalities have been reported. There is an increased risk of spontaneous abortion, and premature births have been reported.
Dr. Edward Lammer, a medical geneticist and consultant to FDA, states,“There is no other medication that poses an absolute risk anything remotely close to this, even medications used to treat cancer during pregnancy”.
Profits over Health
In addition to it’s life threatening side effects, Accutane has been one of the most profitable drugs on the market. It has brought in over $700 million a year for the Swiss company’s creator with 12 million people worldwide having taken it. In 2000, Accutane sales totaled $759.4 million, which accounted for 8% of total prescription drug sales.
It’s no wonder Accutane is as easily prescribed as it is, even in the most acute cases. Think about who profits with this, or any drug when it offers the easy option to treat symptoms only. It’s not the patient!
Get to the Root Cause of Your Acne and Say No to Accutane!
The answer isn’t as black and white as we’d like to think. If we take a step back and look at acne for what it is, like almost every health condition, it is inflammation at the root. Since there are many causes for inflammation, getting to an individual’s cause of acne is a bit of an investigation. It starts with a whole foods anti-inflammatory diet to encourage healthy digestion. This process includes looking at possible yeast infections, pathogenic bacteria and parasites as possibilities. Strong immunity, balanced hormones, blood sugar control, and stress management is also important. In addition, undergoing a comprehensive and supportive detoxification program can help tremendously. At the simplest level, following a nontoxic, noncomedogenic skin regime works from the outside to compliment your internal work.
Sources:
FDA Drug Safety Information
A History of Accutane Regulation in the United States
Kelly Alexandra
I am 50 years old and a Medical Licensed Aesthetician. I suffered from acne from the age of 16 to 31. I was on 5 different antibiotics over the years , retinol products and topical creams. I used shampoo with no oil and basis soap along with other natural things yet nothing worked. I began researching accutane and begged my dermatologist to let me take it but she refused because I was 26 at the time, married and had a 9 year old child. I had my second child and my Dr promised that if my skin did not clear up by then she would allow me to take this drug. I began taking it at age 33 and within 2 weeks my acne was almost gone. I had not one side effect whatsoever. Of course being an intelligent person with a physician who clearly explained that I had to take a pregnancy test biweekly during my treatment due to the side effects that could harm a baby I did. Also, it is explained in detail that once the drug leaves your system you can have a baby just like any one else. I believe 2 years was the time frame at most. I completed a 6 month cycle and my face was clear. I did not have a pimple for over 1 year after that. A few months after that I had a minor breakout and went on a second cycle for one month and it cleared. 27 years later I have beautiful skin and no issues whatsoever. It was the best thing I ever did. My 23 year old daughter has been suffering with acne as I did since the age of 14. I will find a physician who will prescribe it to her because I will not sit back and watch her go through what I did any longer. It is a cure and it is the best thing I ever did. Do not listen to this crap. Anyone can talk people into to believing that an issue they have was caused by something simply because it is on google. I would like to know if the person who wrote this article suffered from acne and is so took accutane.
Lolita
Hello Sarah, I did Accutane two years ago and I still have the symptoms from it (ibs, liver problems, DRY nose, eyes, hair, skin, EVERYTHING) do you know how to detox from it ? Or something that would bring some relief from it? Maybe certain nutrients. Thank you so much, you have the most helpful blog ever, everything I wonder you have an article for it.
George
I went on two full cycles of accutane in my teenage years and my acne still returned. Since then Ive been taking a tiny dosage of one 20mg pill a week for a few years now without rest and the only side effect I recieve are slightly dry lips. I go for check ups every few months and nothing unusual has ever been found. Can a dosage so light still have long term affects?
Kiki
I was prescribed Roaccutane aged 12, had all the side effects, messed up my whole life. 20 years later I am very ill.
Anapaula Coronel
I was prescribed Accutane at my freshman year of high school, cleared up my skin 100%. Acne came back, due to the depo shot I was currently on (my theory). Later on i think it was my sophomore/junior year started it again, 3 months in I became depressed and decided to stop. My senior year of high school it became known I was diagnosed with hodgkins lymphoma and had to received chemotherapy. I am now on my sophomore year of college healthy and cured. My theory is the accutane gave me this result. Could be not the case. But that’s what I blame it on. I was told studies shown that 0.05% got lymphoma in the future after the use of accutane. I could of been that 0.05%, you know?
Brittany
Have you started accutane yet and if so, how is it going so far?
Sunnymc
Some people use isotretinoin (aka Accutane) to treat their cancer so in some cases the benefits can definitely outweigh the risks, especially if somebody has cancer. Yes people should be aware of the possible side effects but it is up to the patient on the doctor to decide the best course of treatment for each patient and if the side effects are worth the risk .
Sarah
Yes, accutane is a chemotherapy drug.
Jason
This author has no clue. I was on accutane twice. Once when I was 19 then again at 23. It works miracles. Self esteem and getting a normal life back are obviously underrated in the opinion of this author. While on this med I had monthly blood tests and was fully monitored. I am now 47 and have no long term effects (other than very few acne scars from my pre Accutant years). Please weigh both sides of this med (the good and the alleged “bad”) before making a decision as well as passing judgemet.
Sarah
Glad you are ok … but SO MANY are NOT ok. Your n=1 example doesn’t mean accutane is safe!
RickItWorked
I was on this medication when I was in my early to mid 40’s … 2 sessions … one for 4 months … another for 2 months. While on the medication, the doctor checked me once a week … doing blood tests, etc and reporting all results to the Hawaii Dept of Health (required as part of any prescription issued by a Hawaii doctor & filled at a HI pharmacy). THE BEST RESULTS ever … for a terrible situation that had plagued me for (on & off) over 20 years! Hard to accept such a gloom & doom story by this writer … apparently the writer believes the use of an effective drug under great medical supervision is not possible. BTW … I am now 68 yo … since the accutane … my body has been cleared of major acne for over 25 years.
Sav
Great article. I completely believe in the what you put in your body is what comes out (acne). I had cystic acne, and every time I went to the doctor to ask for effective non-accutane treatments, they still recommended accutane every time. I gave in as I wanted to be as beautiful on the outside as I felt inside. After I took Amnesteem (later found out the dosage was too high as I had lost 20 pounds over the course of two months), I developed chronic yeast infections which I still get to this day. I was the happiest person I had known before. During the treatment, I developed an anxiety that made it hard to communicate with others. My self esteem dropped really low so much that I considered suicide. I would have never thought I could develop the kind of mindset and depression that I did and still do. I would have rather lived with my acne.
I didn’t think I would be that small percent to get these long term side effects.
Additionally, I have read that one needs to eat a healthy diet( grain free, sugar/ dairy free, processed food free, and basically paleo) for MINIMUM six months in order for the body to fully heal. Seppo Puusa (Acne Einstein) does an excellent job of breaking down health and the chemistry in the body that scientifically relates to one’s acne. After my acne came back post-accutane, his book was extremely informative, and has helped me heal my acne again the natural way.