Did you know acne is the most common skin disorder in the United States, affecting 40 to 50 million Americans?
Nearly 85 percent of all people will have acne at some point in their lives. It can generally begin in the teen years, with more than 40 percent of adolescents being affected due to puberty and hormonal changes, and although it is generally seen as a teenage phase, this couldn’t be further from the truth.
More than 90% of clients I work with struggling with acne are over 30 years old. For some it does go away, and for others it stays, and for many, the first time they experience acne may not be until later in life, from late 20’s to even 50 years of age.
Acne affects individuals not just physically, but emotionally as well. The notion that acne is just a “cosmetic problem” is very off base. Acne is a reflection of something greater happening in the body that is not being corrected. Therefore, the skin continues to lash out in an effort to communicate that there is an imbalance, deficiency, or the mechanics within are just not working as they should be. But this takes time to figure out, and unfortunately, our conventional way of addressing acne tries to do this immediately with topical treatment and/or pills.
Though no matter what age acne occurs, the one thing everyone will feel as a result is pain and embarrassment. Acne affects an individuals confidence, mental outlook, and can greatly impact one’s social life. According to the American Academy of Dermatology, one in five U.S. adults also suffers from acne, and for them the psychological toll is often no less severe.
So the question then becomes: How far would you go to get rid of your acne?
Would you compromise your health for clear skin? Would you gain more weight, lose your concentration, vision or appetite? How about put your unborn baby at risk for severe health consequences? Sounds crazy right? If you have ever experienced acne, you know the desperation one feels, literally being at your wits end to find an answer.
Once the topical products and treatments stop working (or may never have), it’s quite normal to start looking for other options. Go to your doctor or dermatologist, like most people, and you may find they prescribe a little drug called Accutane.
Accutane: The Most Dangerous Drug Ever Created?
Actually, this is no little drug at all, and definitely not something to just accept and take lightly.
The generic name is sold as, isotretinoin, and formerly marketed as Accutane (Roaccutane outside the United States). Other generic forms of Accutane are Claravis, Sotret and Amnesteem. Accutane is part of a class of medications that were originally marketed as chemotherapy drugs. The generic versions of Accutane are just as dangerous as the original.
The medication is a synthetic derivative of vitamin A and works by controlling the oil in the sebaceous glands for those who have not responded to antibiotic treatment.
In 1975 American researchers for Hoffmann-La Roche began studying the chemical, isotretinoin, and found it to be an extremely powerful antidote to acne, unmatched by any other treatment. They found that 85% of patients who took Accutane achieve full remission after a typical course of treatment (about five months). FDA Consumer Magazine pronounced it as “the biggest breakthrough in acne drug treatment over the last 20 years.” It was, and still is seen as a “miracle drug”, but at what cost?
Accutane Side Effects
The U.S. Food and Drug Administration stated:
All patients treated with isotretinoin [Accutane] should be observed closely for symptoms of depression or suicidal thoughts, such as sad mood, irritability, acting on dangerous impulses, anger, loss of pleasure or interest in social or sports activities, sleeping too much or too little, changes in weight or appetite, school or work performance going down, or trouble concentrating, or for mood disturbance, psychosis, or aggression.
Other side effects include:
- Diminished night vision
- Increased bone injuries and concussion risk due to weakened bones
- Severe joint and muscle pain
- Liver damage
- Autoimmune disease
- Red, cracked or sore lips
- Brittle nails
- Unusual hair growth or hair loss
- Fatigue
- Headaches
- Increased reaction to UV exposure
- Nosebleeds
- Peeling skin
- Bleeding or swollen gums
- Slow healing of cuts or bruises
- Dry eyes
- Muscle aches
- Increase susceptibility to colds
- IBS
- Depression
- Aggressive Behavior
- Suicide
- Guaranteed birth defects
Drugmaker, Roche, who created the original version of Accutane has had 13 lawsuits from users who developed inflammatory bowel disease as a result of taking Accutane. In addition, it has been showed in brain scans that there was a 21% decrease in brain activity, leading to depression, suicide and aggressive behavior.
Accutane, which is currently no longer on the market, was only meant to be used as a last resort to treat acne, but prescriptions of its competitors and generic versions are just as health damaging and are being offered for even acute cases of a few spots.
Accutane Heavily Overprescribed Under Different Names
Remember, generic forms of Accutane are still on the market and heavily overprescribed. They are listed as Isotretinoin (originally Accutane), Claravis, Sotret and Amnesteem and are just as deadly.
According to Jennifer Hansen, a 21 year-old taking Accutane who keeps an online Accutane journal, “This medicine has given me my life back. . . . I am now confident, happy and very excited about life. I no longer feel inferior and can actually look people in the eyes.”
This statement sounds like a contradiction knowing the dangerous potential that Accutane has to destroy lives. If Jennifer had tried other natural methods that addressed her real cause of acne, she may have truly gotten her life back, both in clear skin and health, but unfortunately for those who have used Accutane, the consequences may not come until later in life.
Accutane: FDA Pregnancy Category X
The deadliest side affect of them all was announced when the FDA slapped the strongest warning available, as an FDA Pregnancy Category X rating, GUARANTEEING that whether you are pregnant or will become pregnant, taking Accutane can cause birth defects, miscarriage, and death in babies.
According to Julia Green, who wrote the article, “A History of Accutane Regulation in the United States” through Harvard Law School, “One quarter of babies born who have been exposed to Accutane during gestation have major congenital deformities. Those babies born without major malformations frequently develop severe learning disabilities.”
Is this not reason enough to avoid this drug?
According to the FDA’s iPledge system:
There is an extremely high risk that severe birth defects will result if pregnancy occurs while taking isotretinoin in any amount, even for short periods of time. Birth defects which have been documented following isotretinoin exposure include abnormalities of the face, eyes, ears, skull, central nervous system, cardiovascular system, and thymus and parathyroid glands. Cases of IQ scores less than 85 with or without other abnormalities have been reported. There is an increased risk of spontaneous abortion, and premature births have been reported.
Dr. Edward Lammer, a medical geneticist and consultant to FDA, states,“There is no other medication that poses an absolute risk anything remotely close to this, even medications used to treat cancer during pregnancy”.
Profits over Health
In addition to it’s life threatening side effects, Accutane has been one of the most profitable drugs on the market. It has brought in over $700 million a year for the Swiss company’s creator with 12 million people worldwide having taken it. In 2000, Accutane sales totaled $759.4 million, which accounted for 8% of total prescription drug sales.
It’s no wonder Accutane is as easily prescribed as it is, even in the most acute cases. Think about who profits with this, or any drug when it offers the easy option to treat symptoms only. It’s not the patient!
Get to the Root Cause of Your Acne and Say No to Accutane!
The answer isn’t as black and white as we’d like to think. If we take a step back and look at acne for what it is, like almost every health condition, it is inflammation at the root. Since there are many causes for inflammation, getting to an individual’s cause of acne is a bit of an investigation. It starts with a whole foods anti-inflammatory diet to encourage healthy digestion. This process includes looking at possible yeast infections, pathogenic bacteria and parasites as possibilities. Strong immunity, balanced hormones, blood sugar control, and stress management is also important. In addition, undergoing a comprehensive and supportive detoxification program can help tremendously. At the simplest level, following a nontoxic, noncomedogenic skin regime works from the outside to compliment your internal work.
Sources:
FDA Drug Safety Information
A History of Accutane Regulation in the United States
Tena M
You’re article on say no to accutane – is too simplistic. and your advice on getting to the root of the problem. Well, don’t you think that everything that can v=be done has been done by people with acne? Accutane is a last resort medication but it’s not just about the pharma greed. It works and it works extremely well. It can and does change lives for the better. Having said that it is risky and causes massive birth defects. And it’s not just about the skin. If you are going to write an article on why not to take it then you should offer some REAL advice with REAL research about what to do about it. Diet and excersize? Inflammation? What background so you have in dermatology? Show me some real science on why your approach works. Did you try this approach yourself? Do you even have the type of acne that just never goes away? Just say no to nutritionist nurses that don’t know anything about dermatology.
Jan
I accepted the risk of some minor side.-effects when taking Roaccutane as it reduces the output of mucas in the body (dry lips, bleeding nose, aching joints etc).. What i did not anticipate was my blood pressure (which had always been low) rising to unprecedented and dangerous levels. I attribute this to the drug killing off my population of the intestinal bacteria Akkermansia muciniphila which regulate blood pressure and which feed on mucus in the gut. I stopped taking Roaccutane, took Inulin (which Akkermensia feeds on) and now my blood pressure is back to reasonable limits. Yes, Roaccutane works, but at a life-threatening price which I was not prepared to pay.
E
My husband has just passed away. He took isotretinoin in 2008. He had a rare form of bowel cancer. I am almost certain taking this drug has killed my 42 year old husband. Leaving myself & my daughter heart broken. I am definitely looking for answers.
scott sweet
I took accutane back in the early 1980s and as a teen and it worked for me , I was one of the first 100 patience in Michigan to take it , my family could not afford it for me, so I was under experiment to try , I had very bad acne some over a inch in diameter , my nose looked broken do to the acne, I was ashamed to show my face , people made fun of me kids you to ask me whats wrong with your face , had huge zits always pus coming out it was hell for me , this drug cured me and saved me from taken MY OWN LIFE , I have no long term effects none , i have two adult children in there late 20s now and they are normal, so any ways if i had to do it again I WOULD TAKE IT AGAIN, The drug helped me and no scares none on my face, so happy to have had the drug . AND I never had a pimple ever again, it worked for me .
K
I am currently taking Accutane (Isotretinoin) after suffering from acne these past 8 1/2 years. I am mid-20s. Of course I’m worried about the long-term affect of this drug, but having tried long courses of antibiotics and every topical treatment both prescribed and over the counter, I am at the end of my rope. I am vegan and have been for years. I eat very well and have tried every sort of lifestyle and diet change I could find recommended online. My face is so badly scarred from so many years of severe acne that Accutane is my final option. The difference only a few weeks in is better than any result I’ve had in 8 1/2 years. My mood has actually improved because I have hope my acne might clear up! It is not purely vanity. Acne hurts. I am judged constantly. I am scarred. It’s the first thing people see when they look at me. I did not make the decision to start Accutane lightly and, like I’ve said, it is my last hope. I cannot stand people who have never experienced severe acne commenting on the choices of those who have. If some diet or lifestyle change could cure my acne, I think most people would choose to do that rather than putting themselves through Accutane treatment! The side effects so far have not been fun, but they are bearable. Having clear skin will change my life. I have spoken to so many people who have been on Accutane and they are all fine. I don’t dispute it should be an absolute last cause, but please do not try and tell me you can cure my acne with tea tree and meditation, because I have tried it all. Thank you.
Louise
My son 20, took Accutane a couple of years back for his Acne… He is since then having erectile dysfunction, feeling a slight numbness in his genitals and also starting to lose his hair, very devastating for another wise healthy young man. I wonder, would you know of any treatments that may reverse these long-term side effects of Accutane? Or what type of specialist he should see? Or are there other treatments you would recommend, ie liver cleanses, bile cleansing? Does anyone have any positive experiences in treating these side effects they can share? Thank you!
Krystal
I would like to share my story about my experience with Accutane. I started taking the medication in June of 2015 for a short period of time before experiencing several side effects. By September 2015, I had been hospitalized several times and ended up having a splenectomy. My liver was enlarged and my spleen was necrotic, all as a result of the Accutane. This medication is extremely dangerous and for those of you who do not think so, you are in fact mistaken. I feel certain that the manufacturer of this medication is well aware of just how dangerous this medication is.
Laurie
I took Accutane when I was in high school in the 80’s. I still suffer the side effects. I have chronic joint pain, IBS, chronic fatigue, etc. I have 3 sons. All 3 of them have had health problems. My oldest son had brain cancer. They suspect he was born with it, but it was not discovered until the tumor grew large enough to cause pain. He is fine now. My middle son develops unicameral bone cysts that cause spontaneous fractures and the need for surgical bone grafting. My youngest son was born extremely premature, at 23 weeks gestation, and has had a mountain of problems. I have often wondered if their problems are a result of me taking Accutane when I was a teen. I no longer suffer from acne, but I take a completely different all natural approach to skin and health care now. Starting with balancing my hydrochloric acid level in my gut and getting rid of a yeast build up in my body.
Steph Rogers
I take accutane and love it. Other than chapped lips from time to time that I treat with chapstick I’m healthy and happier than ever. It’s possible that those who were effected negatively had other issues already or in combination with the drug. It worked for me and I love it.
Sarah
I am glad you are ok! Perhaps you should withhold your praises for this drug until you are finished taking it and see if you experience any of the negative side effects (read through the comment section on this post to get an idea).
DV
Can somebody please help? I was prescribed Isotretinoin a couple years ago. Now I suffer from bone and muscle aches – I can’t even stand without my legs paining; can’t even write a sentence without my hands hurting. Needless to say it completely hinders my life! But there’s more – depression, hairfall, loss of eyebrows and facial hair, dry skin, dry eyes, dry mouth and lips, elevated liver enzymes, bilirubin, and cholesterol, loss of memory and the list goes on.
I’m still young (24) but I feel like an old man on death bed. I’ve been even contemplating suicide cuz I can’t live this…
Is there any solution ? A cure or way to detoxify? Or am I to suffer like this with death as the only answer?