Did you know acne is the most common skin disorder in the United States, affecting 40 to 50 million Americans?
Nearly 85 percent of all people will have acne at some point in their lives. It can generally begin in the teen years, with more than 40 percent of adolescents being affected due to puberty and hormonal changes, and although it is generally seen as a teenage phase, this couldn’t be further from the truth.
More than 90% of clients I work with struggling with acne are over 30 years old. For some it does go away, and for others it stays, and for many, the first time they experience acne may not be until later in life, from late 20’s to even 50 years of age.
Acne affects individuals not just physically, but emotionally as well. The notion that acne is just a “cosmetic problem” is very off base. Acne is a reflection of something greater happening in the body that is not being corrected. Therefore, the skin continues to lash out in an effort to communicate that there is an imbalance, deficiency, or the mechanics within are just not working as they should be. But this takes time to figure out, and unfortunately, our conventional way of addressing acne tries to do this immediately with topical treatment and/or pills.
Though no matter what age acne occurs, the one thing everyone will feel as a result is pain and embarrassment. Acne affects an individuals confidence, mental outlook, and can greatly impact one’s social life. According to the American Academy of Dermatology, one in five U.S. adults also suffers from acne, and for them the psychological toll is often no less severe.
So the question then becomes: How far would you go to get rid of your acne?
Would you compromise your health for clear skin? Would you gain more weight, lose your concentration, vision or appetite? How about put your unborn baby at risk for severe health consequences? Sounds crazy right? If you have ever experienced acne, you know the desperation one feels, literally being at your wits end to find an answer.
Once the topical products and treatments stop working (or may never have), it’s quite normal to start looking for other options. Go to your doctor or dermatologist, like most people, and you may find they prescribe a little drug called Accutane.
Accutane: The Most Dangerous Drug Ever Created?
Actually, this is no little drug at all, and definitely not something to just accept and take lightly.
The generic name is sold as, isotretinoin, and formerly marketed as Accutane (Roaccutane outside the United States). Other generic forms of Accutane are Claravis, Sotret and Amnesteem. Accutane is part of a class of medications that were originally marketed as chemotherapy drugs. The generic versions of Accutane are just as dangerous as the original.
The medication is a synthetic derivative of vitamin A and works by controlling the oil in the sebaceous glands for those who have not responded to antibiotic treatment.
In 1975 American researchers for Hoffmann-La Roche began studying the chemical, isotretinoin, and found it to be an extremely powerful antidote to acne, unmatched by any other treatment. They found that 85% of patients who took Accutane achieve full remission after a typical course of treatment (about five months). FDA Consumer Magazine pronounced it as “the biggest breakthrough in acne drug treatment over the last 20 years.” It was, and still is seen as a “miracle drug”, but at what cost?
Accutane Side Effects
The U.S. Food and Drug Administration stated:
All patients treated with isotretinoin [Accutane] should be observed closely for symptoms of depression or suicidal thoughts, such as sad mood, irritability, acting on dangerous impulses, anger, loss of pleasure or interest in social or sports activities, sleeping too much or too little, changes in weight or appetite, school or work performance going down, or trouble concentrating, or for mood disturbance, psychosis, or aggression.
Other side effects include:
- Diminished night vision
- Increased bone injuries and concussion risk due to weakened bones
- Severe joint and muscle pain
- Liver damage
- Autoimmune disease
- Red, cracked or sore lips
- Brittle nails
- Unusual hair growth or hair loss
- Fatigue
- Headaches
- Increased reaction to UV exposure
- Nosebleeds
- Peeling skin
- Bleeding or swollen gums
- Slow healing of cuts or bruises
- Dry eyes
- Muscle aches
- Increase susceptibility to colds
- IBS
- Depression
- Aggressive Behavior
- Suicide
- Guaranteed birth defects
Drugmaker, Roche, who created the original version of Accutane has had 13 lawsuits from users who developed inflammatory bowel disease as a result of taking Accutane. In addition, it has been showed in brain scans that there was a 21% decrease in brain activity, leading to depression, suicide and aggressive behavior.
Accutane, which is currently no longer on the market, was only meant to be used as a last resort to treat acne, but prescriptions of its competitors and generic versions are just as health damaging and are being offered for even acute cases of a few spots.
Accutane Heavily Overprescribed Under Different Names
Remember, generic forms of Accutane are still on the market and heavily overprescribed. They are listed as Isotretinoin (originally Accutane), Claravis, Sotret and Amnesteem and are just as deadly.
According to Jennifer Hansen, a 21 year-old taking Accutane who keeps an online Accutane journal, “This medicine has given me my life back. . . . I am now confident, happy and very excited about life. I no longer feel inferior and can actually look people in the eyes.”
This statement sounds like a contradiction knowing the dangerous potential that Accutane has to destroy lives. If Jennifer had tried other natural methods that addressed her real cause of acne, she may have truly gotten her life back, both in clear skin and health, but unfortunately for those who have used Accutane, the consequences may not come until later in life.
Accutane: FDA Pregnancy Category X
The deadliest side affect of them all was announced when the FDA slapped the strongest warning available, as an FDA Pregnancy Category X rating, GUARANTEEING that whether you are pregnant or will become pregnant, taking Accutane can cause birth defects, miscarriage, and death in babies.
According to Julia Green, who wrote the article, “A History of Accutane Regulation in the United States” through Harvard Law School, “One quarter of babies born who have been exposed to Accutane during gestation have major congenital deformities. Those babies born without major malformations frequently develop severe learning disabilities.”
Is this not reason enough to avoid this drug?
According to the FDA’s iPledge system:
There is an extremely high risk that severe birth defects will result if pregnancy occurs while taking isotretinoin in any amount, even for short periods of time. Birth defects which have been documented following isotretinoin exposure include abnormalities of the face, eyes, ears, skull, central nervous system, cardiovascular system, and thymus and parathyroid glands. Cases of IQ scores less than 85 with or without other abnormalities have been reported. There is an increased risk of spontaneous abortion, and premature births have been reported.
Dr. Edward Lammer, a medical geneticist and consultant to FDA, states,“There is no other medication that poses an absolute risk anything remotely close to this, even medications used to treat cancer during pregnancy”.
Profits over Health
In addition to it’s life threatening side effects, Accutane has been one of the most profitable drugs on the market. It has brought in over $700 million a year for the Swiss company’s creator with 12 million people worldwide having taken it. In 2000, Accutane sales totaled $759.4 million, which accounted for 8% of total prescription drug sales.
It’s no wonder Accutane is as easily prescribed as it is, even in the most acute cases. Think about who profits with this, or any drug when it offers the easy option to treat symptoms only. It’s not the patient!
Get to the Root Cause of Your Acne and Say No to Accutane!
The answer isn’t as black and white as we’d like to think. If we take a step back and look at acne for what it is, like almost every health condition, it is inflammation at the root. Since there are many causes for inflammation, getting to an individual’s cause of acne is a bit of an investigation. It starts with a whole foods anti-inflammatory diet to encourage healthy digestion. This process includes looking at possible yeast infections, pathogenic bacteria and parasites as possibilities. Strong immunity, balanced hormones, blood sugar control, and stress management is also important. In addition, undergoing a comprehensive and supportive detoxification program can help tremendously. At the simplest level, following a nontoxic, noncomedogenic skin regime works from the outside to compliment your internal work.
Sources:
FDA Drug Safety Information
A History of Accutane Regulation in the United States
Andrew B
This article appears to be written by someone who has never had Cystic Acne. For me (28 year old male) who has had SEVERE boils acne/boils on my shoulders over the last 15 years, I have come to accept one of the two options suggested by my dermatologist:
1) Topical and Deep tissue surgery to help repair muscle tissue/skin damage from the boils & help reduce the boils/cystic acne over time. (with no guarentee it will work).
2) a 6 month stint of 40 mg daily dose of Isotrention resulting in mild to extreme discomfort/dry skin for 6 months.
Based on the costs and risks involved, I’m going with option 2. If you were provided these 2 options which one would you choose?
Hawaiian
I’m 43 years old and have suffered from severe acne since I was 13 years old. People said back then: “Oh, you’ll grow out of it!” They were wrong. Nothing worked until I was introduced to Accutane in 1990. In my opinion, it’s the best acne drug hands down. The only side effects that I had were the typical chapped lips, dry skin, and slightly elevated cholesterol; however, these side effects are easily managed by using chapstick, moisturizer, and proper diet. People say that Accutane causes severe depression. That notion is debatable because I was severely depressed when I wasn’t on it. I missed out on so many parties with friends and family because of my cystic breakouts. I was embarrassed to go out in public. Claravis is the bomb.
Tianne
I developed acne at 15. I am now 31. Within a year it was cystic and I had pitted scars all over my face. I was bullied relentlessly through school. I applied topical medications that left my skin raw. I was taking antibiotics every day… for eight years straight. I suffer from depression and anxiety that I believe is directly associated with my acne and subsequent experiences. I have not left the house without a mask of foundation to cover as much as possible, in over 15 years. I have attempted suicide twice whilst at school.
I have finally resorted to this drug Accutane having feared it for so long… I am 3 months in and my skin is becoming clearer. Yes, the side effects are crushing. I cannot get to the top of the stairs without ending up on all fours. But I can see the improvements in my skin. After having the acne destroy my life over the past 15 years… the alternative to not taking the drug would have had me far worse off. It’s worth putting into context.
Thanks
Renee
I’ve had serious problems with chronic fatigue, unable to gain weight and digestive issues for the past 18 years since taking accutane. These symptoms developed the year following my course of medication and have affected my life greatly. Countless doctor visits only gave me the information that my white blood cell count was extremely low and this was blamed on a ‘mystery illness’ that was never identified. I now understand what the cause was. The immediate symptoms I had with accutane was personality changes, anger and depression with suicidal thoughts. I was 12 years old and had no reason to be depressed.
A peterson
It should be a last resort med. my son was given as the very first med he took after trying a topical cream. My son didn’t have very bad acne. He had a friend at school rave about the results and asked about taking it. I took him and he told the dermatologist that is what he wanted and she gave it to him. He committed suicide 6 months later.
Sarah Pope MGA
I am so very sorry for your loss. Such a tragedy. More people need to know about the terrible side effects of this drug.
A peterson
I wish there were more article like this. I let my son take this drug and now he is dead. His acne never met the standards that the Dr’s should have put h him on this drug. I never in a million years thought a drug could do the kind of damage this one has done. My son suffered from many of the side effects and took his life his senior year of high school. He was a fun loving and out going boy who changed once taking Accutane. This drug is way over prescribed. Thank you for writing this article. I wish we could have some studies from those who did have side effects and lived to tell about them.
Gary MI Gardner
I am a 64 year old white male. I had acne pretty bad as a teenager. It stayed with me my whole life and eventually I developed rhinophyma. The oil glands in my nose produce way too much oil. I had tried accutane as a young man and it became harder and harder to find a doctor that would prescribe it. It works great and I have been using it about 6 years.
I no longer have a swollen red nose and am much more confident in public. I have found it through other methods now. It truly is a miracle drug. I have had no side effects.
Gary in Houston TX
Brooke
I hate articles knocking accutane. This drug has saved thousands of lives. If you have never had severe cystic acne, then you do not understand the severe depression it causes. I had acne from age 13 until 15 when I finally was given accutane. My acne was gone in 4 months and has NEVER come back. I’m now 38 years old with no ill effects from it. The worst side effect I had was dry lips and skin. My son is 10 (perfectly healthy) and if he gets acne, I will demand that he is given this and not made to suffer for years like me.
JJ
I took it at 26, for 8 months at 80 mg/day, and it worked like a charm. I’m male and weigh/weighed about 170. I had very minimal side effects: mainly dry lips, eyes, and skin. I also experienced moderate back and joint pain that was very infrequent and would go away after about an hour or so. My acne hasn’t returned since, and I have yet to experience any long term issues.
The potential side effects for this drug are very real, they are published, and you should be aware of them before you take the drug. However, taking the drug is a choice. I chose to do it and the result were spectacular. I highly recommend it.
Madeline Matelich
In 1981 I had a radial keratotomy (RK). In 1982/83 I made an appointment with a dermatologist for a cure for my cystic acne and he advised me that there was a new medication on the market that he would prescribe for me and it was called Accutane, I asked him about any side effects and he said that I should not question it but be thankful, in my case, for this new medication. He admitted that he had not prescribed Accutane for anyone who had an RK and that his sister was going to have that operation on her eyes, too. He was going to put her on Accutane, also.
I took the mediation as he advised and noticed some horrible side effects. I called the doctor and told him that my eye sight was getting extremely limited and my skin looked like a reptile’s. You could tell that he was frightened and told me to not take anymore of the Accutane. The doctor had quite an inflated ego until he heard about my side effects and it burst his bubble. He then told me that there was nothing more that he could do for me and I never saw him again.
Recently I saw an article about Accutane causing tinnitus and I realized that that was the time I had noticed that I had tinnitus and still do at age 75. I have also developed depression at that time and still suffer from it.
So this is to advise members that it all started back in the 80s.